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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17ac153f7573b5b6ad605a55f6e5bb431f336e8e955fc939afb6ace1a3321e60' 
  AND token = 'nZkmZSU0P5mIBO0QRj/m4YgMn0lxhZ+fYD93a/ka10o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}