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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cf5b0a9074b99bde1d8dfac3468ed61c257ed1347f7adbc2ea68bb2a8615859' 
  AND token = 'DhcyvWQRamXVs5R7E7ZvwFNyXXmf6YOhrsg3dA99xfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}