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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '285206f099a565b57392ad3f2c6397eba4c395cbe0b937e9dc07748df23e7ffd' 
  AND token = 'n22TOw3nYNx5ndFdYGcGIOOaH7TUYs5YUx4Y/aBaSj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}