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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '134f3d0e7d5bbf856b562396f55b1b81149d141e3bd7a948ecc10bef86262e89' 
  AND token = 'aZcC5S8/gnU0buDDehNfA8VycsdS7j5gM8MMo48mGXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}