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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '459db498ad90fd9fcc33e26950c94b4bf72ac967091f4354c53b7ca8786a446a' 
  AND token = 'SvVZaQ2Li0r8jC91t+iE11rBVvmAfeqWGI0rSee6Sc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}