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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f5c104623acb15d7537d4456d355a545d369c157a5aa5389fc0254766cd489' 
  AND token = 'nhmE4UhdMk4mgjyMYnazgqix80eTuaPKu3IA2P5rU5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}