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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb4988d2af29cd0a4e7e60d431d1331cac9115fb898175649977181ef0432b22' 
  AND token = '/6Ql1Hnl1ryKE8QaBhAy/hOa6/b0hpTlrkU/7BtGmHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}