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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f6dc480a9c8f40d4672aa1091f0cc60fecf9313a1b0f9b4acbec10e03a6ec8b' 
  AND token = 'QDJoByhIM0nnHQK00K6NCsXkQFgtrcazFTqKcDV8klU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}