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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a42ad5359be6c42ae87c9800df28802b0be40347d341d90af41e4eb9a3b8ddce' 
  AND token = 'd5+Eo5RsEHGBPLDO5c/oUVZpBcdOXWaEX4lk1yJJTWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}