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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '404649a84a52cc001293456b7b8dffd1b808796cff32e00e2ce16db1649ba40e' 
  AND token = '+d/2wYuTRflB57UBJjuTO9OR8NIXzw1EioNBTtvVjek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}