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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f485c7660aefdbb1aa431632ed3c4d28194a5d37c19c085e12aabd0b7d6dd06' 
  AND token = 'oZ22ObFhuggzhoNEV6PWfcIpXG3WKtA0YfF7O+rtaws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}