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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da4c8a3a70ef201201a02845167c3975247ffa946ed62780c443ca8366881c0a' 
  AND token = 'nY7At7Zzuq2Z/rbrZ7wq7PW4LP/uwxU++L7E2phwZUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}