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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e072c533e83ec58989d30a6f3b6cca9e9856776dad4195883a203e15568f33d' 
  AND token = 'NAsbCqE+fd1irai/vRpXoCQgO0rPzTZZirX9jI7y1x8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}