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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14e6eea850e1a931e0b966ea4bd384d43266c671fce814acf455961991dea2a4' 
  AND token = 'BS8/ASfVsuvnOmd7W2ALkaA3AlIivD7QXxma1oVLSRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}