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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a6a3ec110232a1d80989aa775cacefa7fdf5059a7c720475db0aca6123d5545' 
  AND token = 'JPSBbw1qwAgBSxkFS/3mU0sZoALeZtSLwe2K6jx8h80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}