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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4cd9303dcebb9d1bda9b6b058043a024c38adb0bdae25a880b83358c6c9056d' 
  AND token = 'fbIxQ6hrsj/w0BRf4gdCIg06vm1LQw7sGEcJWWeC8BA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}