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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1b98f53195392171802a6907cb154e1a102cdb1f80f434930edba1b1d061414' 
  AND token = 'DpktX2wrJA0GbjyFvfp+DhIN+svQoWde0e5GHDcMmT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}