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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1256223dcb44b15360acd3808b56f0925b0492ec038c6292d203baa965e58a7e' 
  AND token = 'CEXVA+FZnK+ajnv9w7H6xYVNwiJJ8Gd9lOec+tnk13g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}