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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '429b54a612040cfed707b286d0f13921bdd7dbb9c01d22b4c7fd86fc1d268628' 
  AND token = 'k91qiZ9Gu+9AV+i96DUZaBxuvb3lbkBqG8DnB16V1YE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}