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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bd152238fae69f280aa215047e6a28620aa613d4ace2abf33c2f6fb81f6b1f7' 
  AND token = '8BTkq6TDzUd0L2LLjIXrCMSPFhnT4RVvaxMH4qjCaXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}