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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a6767f2df6949674269fb76ecfae5b26fc198556cc051be61379fa26588803d' 
  AND token = 'irggZLSYL2wgjzE3w5+g/fH3KKarHwm0NdyOaHcJ6oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}