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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '851a12624faf727735d01b82110a48131617d96021a76d893bb8252020808a34' 
  AND token = 'gt75VgmCgCOf96akDgEpH4llTADUckVf4t0y86aPcts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}