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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f67f37ec3cbbbd48b4cd451ae3d98450f941de20515021cfa64bfc16b9133bb' 
  AND token = '0EsVOEWefVt2qA46PbBIpRDZbK7AQudXkUIOYelaBsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}