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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ec5a5d0ac3c3975531f3d001f7545cc0af9299e400679dc9cf7bfb0b0470d7' 
  AND token = 'UOX8gdtGA+i1x9lUZI+8hxkxSRznnSR6M+IFbrFi28g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}