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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0ecbf319c7acde6e212fd76c3085c9998ebdfaf8204d4b586b77f4b5721a071' 
  AND token = '4540PN/ZhXm17qq5CbFS9DXNccD+oTBdrBHuH2nA1qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}