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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9c31866160ba1e0217fd92c6f2958eb3606a8a7417a6ecff13052155d378aab' 
  AND token = 'JGf5BYF/M7b2QSfx4FVlrpJ3gflTt08kcuyg81h6uTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}