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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20a971b9b84b295be7fffc7feac1e8a9c8fb168e22403ca62c0cd76b74503843' 
  AND token = 'sixVbTFR+ZdJCrZrQ6ZH0nE/MgeXPohiT1zRbESBQyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}