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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67b2e54cf1f5164d9c7c573166c85684f692f7e69569871057254c9c46b85608' 
  AND token = 'TFgE6+C+vCXalDlx6mGU6wgiF5WyGh4UVPctRI6O6U8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}