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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eef1cc62f4d4684e9eeb3bbb1417dfae012ae108f881393cbce36e1e280ac6a' 
  AND token = 'fWx5tJQ9GUCJF17+HsZoYFp8nfyJh8X7pjItc7dSa1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}