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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdb78040a57546fef63f144c1b2a59e8368cbe7da393d6ee391a40754ea487c8' 
  AND token = 'ELfkJP6xHZalBNRqVe0UFa+Xt6TTAnhvL2xso3bAPLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}