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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4176da82c11005ededb4258fa7864e351ad9e675d0cf4633152fd34e75a2a8d8' 
  AND token = 'exeA7GizV8rKfOkjnEkQGmSH7o+vyPFOOk7nt2tjZm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}