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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f953e512f8e4d97f8069087489700d8d238baa67721800927546310f56e56e9c' 
  AND token = 'aNhu7VnqhF5yUUkFZX59NqwzOqBHODFSxBKeg69Xevc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}