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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '880497011ad9e8c58a04b4e19cf54eedb51bf6f3341c5ce06dfad492e22fe657' 
  AND token = 'PfGz+mNgL0XYcLtcNiXfJOwy0XLn1cJ3LsKPo0n0CUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}