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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8e4452df4e21a9cb741895cc7c91f9694d31dc144abffbe575ec90d73fba4bc' 
  AND token = 'wUn+YWUsoKF5VKVgW9qyZy+6aP0bAb5tADFV3qQ1BTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}