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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80f8566ef74fd17edc51e4018535817f2b8d6596995ebad59fc196d0a842ad5a' 
  AND token = 'aHmjamBwXhDXN6H5PjzXmr6To955eTKu1ALldsHw+fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}