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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd83b2b4808be1792a4fa4e2abf831dc3f27db6e16c09c8a0db56aaebf646d43' 
  AND token = 'rMqJp2l08sr054rwwjRVLM4j0+NZgrpXrRYdSGG7PXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}