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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e1807e3333c8bd15898b3e8a060c85641237fc58ca59d64d02c0ae57dfd2a01' 
  AND token = 'Y7b2ENgFn/Q7tHYeVBfhqzTXli3QoKog8y1yjXvF/7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}