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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9779c1959899968cdc899aac13b57c991cfe55f338bf77a5d1354fa5cbfded4' 
  AND token = 'xvHInWLORGMuCA5aQtAVZSjywBV68zYLHDU2sh93rQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}