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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8478b80ee6ac89b5a3259639f41724ca2e813355ea52ca6de96e46035e1efb70' 
  AND token = '/+jQ5tuMQ8mrkR+LSPzmDBxcxWgCD5Jjk7xOzKiEKUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}