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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b9a4b130f021632400891e46299c00e345064bf79be03be295597a8292a837c' 
  AND token = '61ckz363KIkRXeBURqJO1yyzd9440I2WuxfGgMtl40Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}