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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd7b9785837ba1caa7b50c3d9a83e3411f032ab0867070e51c6e5caab110e122' 
  AND token = 'PzU6zLbdotrmZsNvAewsfDhSAq8AxZLC08qeG7HcOtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}