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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29e991f5ad85d5f73e4e7707e93c0e6b9c393ea62684880caa616181105130d8' 
  AND token = 'S0ltLWTO8daoy2v3iySAlx4aTNElUZLnJUT4uTNn2xU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}