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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c728802ca30971eafbc615cf2a7b1da8b3cf1e782e000ae604cadcbcc951961' 
  AND token = 'CXAgftj/oO9B6RxgK2qpRYycSNPahYzLsFZ/rCSw9dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}