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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd59076ffc44d826f2ee8fef50da1b7c7554cdb545c133fc820151de9161e9c42' 
  AND token = 't6vOdf8RTfb+H3NJauII2ONs0NW/6QQnXhCdXo+3wU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}