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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0260c455da60de4059d8a37b269a7a7fad26f56f19e90e34cb26d25471cd27d' 
  AND token = 'EG+wEwWZ0iLBLDvY0f5Wm/bFu4z93RHNEObxHboeubE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}