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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de32b166a8fe9efcee9c60a73a2baf55cd3741ef2aa1a37ce965b8acaffeaa73' 
  AND token = 'kcVP7Aab4jqajaxd0jRgSLpP1PBN44jialFB9A+tXgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}