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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c8a90a5b92d07b6d2abf725368165475be8cfff3179dc9c3536ad3561ec0ed5' 
  AND token = '4xPm8MYJ5XcORLJFTXl2slIiiljc+ZTl9YoP89zJv68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}