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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9aa441ff82e9273cfd2f9b6f707abeed704a5213f1f197ba7d33568ba1e527' 
  AND token = 'sttvk/peohx2ek7WkqE5tqildso2Y3IZo8nO15oZOGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}