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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0aca115bc33b34d23249189035f8ce6052f7cda15036e7d619f6c735d21bb6e' 
  AND token = 'mxFys/QofCGhHDFf3CfrcShZ7tDHHa0/HwdACB2KLDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}