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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df84ff9fa6d8529dcf6671b486f17e1fdca5afa7318b104b3d4516fff721b648' 
  AND token = 'UYCh0DhBmEeC9laEkfa8WtX+6d8wrslmp1tOCMMQqjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}